Class I – Super-Potent / Ultra–High Potency

Topical steroids in this class are the strongest available and are often prescribed for short-term use on thick skin areas like the palms or soles. Due to their potency, they carry a higher risk of side effects and withdrawal. Always use with caution and insist on close medical supervision.

Clobetasol propionate 0.05% – Clobex, Olux (foam), Temovate, Cormax (US); Dermovate (UK), Cloderm (CLP)

Augmented betamethasone dipropionate 0.05% – Diprolene (US/Canada)

Diflorasone diacetate 0.05% – ApexiCon, Maxiflor, Florone (US); Psorcon (US)

Fluocinonide 0.1% – Vanos (US); also Lidex (0.05%)

Halobetasol propionate 0.05% – Ultravate (US); Lexette, Bryhali (US)

Flurandrenolide 4 mcg/cm² – Cordran Tape (US)

This information was gathered from trusted medical and dermatology sources to help you better understand your medications:

• National Eczema Association

• National Psoriasis Foundation

• American Academy of Family Physicians (AAFP)

• EczemaGuide.ca

• Medscape

Note: Each medication listed may appear under multiple brand names globally. This guide includes international variants where available.